Clinical and microbiological features of chronic sinusitis in patients with type 2 diabetes mellitus
DOI:
https://doi.org/10.57231/j.ejohns.2025.4.1.018Keywords:
type 2 diabetes, chronic sinusitis, ENT organs, paranasal sinusesAbstract
This article highlights the results of clinical and microbiological indicators of chronic sinusitis in patients with type 2 diabetes mellitus (T2DM). Demographic indicators, clinical forms of chronic sinusitis, microflora indicators from secretions from the nasal cavity in patients with type 2 diabetes mellitus and chronic sinusitis are analyzed in detail. Purpose: to analyze the results of clinical and microbiological indices of chronic sinusitis in patients with type 2 diabetes mellitus. Materials and methods: A survey of 130 patients was carried out, of which: 80 patients (1st group, main) - with chronic sinusitis against the background of type 2 diabetes mellitus, 50 patients (2nd group, control) with diabetes mellitus without chronic sinusitis, who were treated at the Republican Specialized Medical Center of Endocrinology named after Ya.Kh. Turakulov. Results: Analyzing the results of clinical and laboratory studies of patients with chronic sinusitis against the background of type 2 diabetes mellitus (group 1), it can be concluded that the studied parameters reflect the activity and severity of the inflammatory process in the paranasal sinuses. Conclusions: Distinctive clinical signs of chronic sinusitis in patients with diabetes mellitus are: rapid development of the underlying disease, systemic inflammatory response syndrome. This leads to the development of complications and even an unfavorable outcome of the disease, especially in patients with insufficient glycemic control. The main group of patients is characterized by a higher prevalence of overweight and obesity, family history of type 2 diabetes, and low physical activity compared to the comparison group. In patients with type 2 diabetes mellitus, productive (35%) and exudative forms (32.5%) of chronic sinusitis were more common. An important principle of pathogenetic therapy is constant monitoring of blood glucose levels and etiotropic treatment that directly affects the causative agent of sinusitis.
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